Table 2.

Concordance of PKA scores obtained from manual and semiautomated image (ACIS) analysis

Manual	Image analysis		KS (P)*
	<Q1 (101.7), n (%)	≥Q1 (101.7), n (%)
Negative (0, 1)	77 (25)	103 (33)
Positive (2, 3)	1 (<1)	132 (42)	0.38 (<0.0001)
Low (0, 1, 2)	78 (25)	176 (56)
High (3)	0	59 (19)	0.14 (<0.0001)
	<Median (111.8)	≥Median (111.8)
Negative (0, 1)	144 (46)	36 (12)
Positive (2, 3)	12 (4)	121 (39)	0.69 (<0.0001)
Low (0, 1, 2)	156 (50)	98 (31)
High (3)	0	59 (19)	0.38 (<0.0001)
	<Q3 (128.0)	≥Q3 (128.0)
Negative (0, 1)	177 (57)	3 (1)
Positive (2, 3)	57 (18)	76 (24)	0.59 (<0.0001)
Low (0, 1, 2)	229 (73)	25 (8)
High (3)	5 (2)	54 (17)	0.72 (<0.0001)
	<135.5	≥135.5
Negative (0, 1)	178 (57)	2 (<1)
Positive (2, 3)	80 (26)	53 (17)	0.42 (<0.0001)
Low (0, 1, 2)	240 (77)	14 (4)
High (3)	18 (6)	41 (13)	0.66 (<0.0001)

^*KS = κ statistic and P values are from two-sided tests.