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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Thromb Res. 2009 Jan 30;124(3):311–317. doi: 10.1016/j.thromres.2008.12.031

Table 2.

Effect of quartile of leukocyte count on platelet reactivity before and after aspirin (ASA) treatment*

Quartile (Q) of Leukocyte Count: Median [Interquartile Range]
Q1: 4.2 [0.8] ×103 cells/μL Q2: 5.4 [0.6] ×103 cells/μL Q3: 6.6 [0.8] ×103 cells/μL Q4: 8.6 [1.8] ×103 cells/μL
Collagen aggregation pre-ASA (ohms)
Collagen aggregation post-ASA (ohms)		 18.1 ± 4.4
5.9 ± 5.1		 20.0 ± 4.8
6.3 ± 5.1		 21.5 ± 5.1
6.5 ± 5.4		 23.4 ± 6.1†
7.6 ± 5.8†
ADP aggregation pre-ASA (ohms)
ADP aggregation post-ASA (ohms)		 11.5 ± 5.2
11.1 ± 5.2		 12.6 ± 5.3
12.0 ± 5.6		 13.3 ± 5.7
12.7 ± 6.2		 14.9 ± 6.6†
15.6 ± 6.8†
Arachidonic acid aggregation pre-ASA (ohms)
Arachidonic acid aggregation post-ASA (% >0 aggregation)		 14.7 ± 5.4
4.4		 15.8 ± 5.9
3.8		 17.2 ± 6.6
3.4		 19.7 ± 6.9†
9.2†
Tx-M pre-ASA (ng/mmol creatinine)
Tx-M post-ASA (ng/mmol creatinine)		 194 ± 430
35.0 ± 40.1		 170 ± 396
40.4 ± 55.1		 326 ± 1118
52.4 ± 113		 446 ± 2122†
77.5 ± 414†
*

Data are presented as mean ± SD except Arachidonic acid aggregation post-ASA, which is presented as percent.

ASA = aspirin; Tx-M = urinary 11-dehydro thromboxane B2

†

P< 0.0001 for effect of quartile by analysis of variance