Sedimentation velocity analysis of PKR binding to scTAR dimer. Plot of normalized g(s*) distributions for 0.3 µM scTAR dimer (red), and 0.3 µM scTAR dimer plus 0.15 µM PKR (magenta), 0.3 µM PKR (cyan), 0.6 µM PKR (green), 1.2 µM PKR (blue) and 2.4 µM PKR (black). The corresponding values of sw obtained by integration of the g(s*) distributions are: 4.0 S (0 eq. PKR), 5.0 S(1 eq.), 6.0 S(2 eq.), 6.8 S(4 eq.) and 7.5 S (8 eq.). Measurements were performed in AU200 buffer at 20 °C and 40 000 RPM.