Symptom burden |
Pain |
Anxiety |
Depression |
Sleep dysfunction |
Obstructive sleep apnea |
Restless leg syndrome |
Narcolepsy |
Insomnia |
Nutritional imbalances |
Weight changes |
Changes in caloric intake |
Fluid and electrolyte imbalances |
Motility disorders |
Physical function changes |
Decreased physical activity |
Decreased physical conditioning |
Medical issues |
Anemia (from various etiologies) |
Other comorbidities |
Infection |
Cardiac dysfunction |
Connective tissue diseases |
Pulmonary dysfunction |
Renal dysfunction |
Hepatic dysfunction |
Neurologic dysfunction |
Endocrine dysfunction |
Hypothyroidism |
Hypogonadism |
Diabetes mellitus |
Adrenal insufficiency |
Medications |
Sedating agents (hypnotics, narcotics, neuropathic agents, etc.) |
Beta-blockers |
Supplements (homeopathic agents) |
Other (drug interactions and other medication side effects) |
Cancer treatment effects |
Chemotherapy |
Radiation therapy |
Surgery |
Bone marrow transplantation |
Biologic response modifiers |
Hormonal treatment |