Table 4. Anti-CS and anti-HBs antibody titers after each dose and at 12 months post Dose 3.

	RTS,S/AS01E			RTS,S/AS02D
	N	mean	95%CI	N	mean	95%CI
Anti-CS antibodies:
Screening, all	85	0.3	0.3–0.3	84	0.3	0.3–0.3
- pre HBV	40	0.3	0.3–0.3	40	0.3	0.3–0.3
- no pre HBV	37	0.3	0.3–0.3	39	0.3	0.2–0.3
Post Dose 2, all	74	80	63–101	74	58	46–73
- pre HBV	35	109	79–152	34	81	57–114
- no pre HBV	31	50	35–71	36	44	33–59
Post Dose 3, all	73	207	172–250	73	183	151–223
- pre HBV	35	238	187–302	36	201	145–278
- no pre HBV	31	170	122–238	33	164	128–209
Month 14, all	58	16	12–21	54	18	13–26
- pre HBV	29	15	10–23	29	18	10–32
- no pre HBV	23	17	10–28	21	17	10–29
Anti-HBs antibodies:
Screening, all	85	45	25–80	84	19	12–29
- pre HBV	40	284	127–637	40	61	30–124
- no pre HBV	37	8	5–11	39	6	4–9
Post Dose 2, all	74	9228	4676–18210	74	3838	2036–7237
- pre HBV	35	79610	43152–146869	34	22946	10115–52053
- no pre HBV	31	1095	562–2135	36	770	385–1540
Post Dose 3, all	73	26330	16578–41821	73	20068	13636–29533
- pre HBV	35	94879	56708–158741	36	48279	28412–82038
- no pre HBV	31	7982	5534–11511	33	8292	5233–13138
Month 14, all	58	6769	4338–10561	54	5236	3421–8012
- pre HBV	29	17851	10235–31136	29	8408	4467–15825
- no pre HBV	23	2539	1723–3746	21	3100	1708–5625

Values are geometric mean titers and 95% confidence intervals expressed in EU/mL. N values for pre HBV and no pre HBV do not match up to the total due to some missing values on the pre HBV status.