Figure 4.

Effect of ZnSO₄ and/or carmustine (BCNU) on learning of rats. Data are presented as mean ± SEM (n = 10) and analyzed using Graph Pad Instat software by one way ANOVA followed by Tukey Kramer post-test. ZnSO₄ was injected as a single dose (0.1 µmol/10 µl saline, i.c.v). BCNU was injected in a single dose (20 mg/kg i.v). Learning was assessed by using radial arm water maze where the number of errors for each group was calculated in 12 trials to indicate learning behaviour. (a–c): Indicate significant differences from control, BCNU-treated and ZnSO₄-pretreated-BCNU-treated groups respectively at p < 0.05.