Table 1. Summary of dimensions, biochemical and histological parameters of muscle strips in different study groups.
| (# preps) | Sham | Trabeculae | Neonatal | Graft | Remote (grafted) | Remote (non-treated) | Scar (near graft) | Scar (vehicle) |
|---|---|---|---|---|---|---|---|---|
| Length (mm) | 1.1 ± 0.1 (14) | 1.0 ± 0.1 (16) | 1.4 ± 0.1 (23) | 0.9 ± 0.1 (10) | 1.1 ± 0.04 (17) | 1.0 ± 0.1 (13) | 0.9 ± 0.1 (6) | 1.1 ± 0.1 (10) |
| Width (μm) | 197.8 ± 10.6 (14) | 172.2 ± 20.8 (16) | 235.2 ± 12.9 (23) | 183.5 ± 6.9 (10) | 216.4 ± 8.5 (17) | 189.1 ± 10.6 (13) | 196.2 ± 13.9 (6) | 171.6 ± 15.1 (10) |
| Thickness (μm) | 199.3 ± 18.4 (13) | n.a. | 148.3 ± 4.1 (20) | 197.2 ± 10.1 (10) | 219.7 ± 6.2 (17) | 193.8 ± 10.8 (12) | 171.3 ± 22.0 (6) | 209.7 ± 10.9 (9) |
| Fmax (mN/mm2) | 42.8 ± 8.0 (14) | 58.6 ± 10.2 (12) | 7.8 ± 1.9 (21) | 4.7 ± 0.9 (8) | 54.1 ± 8.2 (7) | 41.8 ± 8.4 (13) | 0.0 ± 0.0 (5) | 0.1 ± 0.1 (10) |
| Maximal ktr (s-1) | 14.2 ± 1.3 (14) | 13.4 ± 1.2 (12) | 7.7 ± 0.5 (19) | 7.8 ± 0.8 (8) | 11.8 ± 1.1 (7) | 11.7 ± 1.0 (13) | n.a. | n.a. |
| pCa50 | 5.41 ± 0.03 (14) | 5.39 ± 0.04 (7) | 5.70 ± 0.06 (7) | 5.69 ± 0.07 (6) | 5.64 ± 0.10 (7) | 5.45 ± 0.04 (12) | n.a. | n.a. |
| nH | 5.0 ± 0.6 (14) | 3.0 ± 0.2 (7) | 2.1 ± 0.2 (7) | 3.5 ± 0.8 (6) | 2.5 ± 0.2 (7) | 5.8 ± 0.9 (12) | n.a. | n.a. |
| Stiffness (mN/mm2) | 273.3 ± 100.1 (4) | 585.6 ± 216.7 (7) | 38.5 ± 9.1 (17) | 452.8 ± 155.5 (8) | 596.1 ± 213.0 (12) | 469.5 ± 75.9 (11) | 4676.2 ± 1380.3 (5) | 3730.4 ± 1339.8 (9) |
| Passive Fmax (mN/mm2) | 54.7 ± 20.1 (4) | 119.8 ± 43.3 (7) | 7.6 ± 1.8 (17) | 90.0 ± 32.1 (8) | 119.8 ± 44.2 (12) | 91.4 ± 14.6 (11) | 920.9 ± 274.2 (5) | 736.4 ± 259.6 (9) |
| Passive force at 4-min (mN/mm2) | 29.4 ± 11.3 (4) | 59.5 ± 23.2 (7) | 4.4 ± 1.2 (17) | 33.8 ± 11.4 (8) | 61.0 ± 20.1 (12) | 51.4 ± 8.0 (11) | 618.8 ± 220.9 (5) | 409.7 ± 156.6 (9) |
| t50d (s) | 2.7 ± 0.2 (4) | 1.9 ± 0.3 (6) | 3.4 ± 0.3 (13) | 1.3 ± 0.3 (8) | 3.3 ± 0.3 (12) | 3.4 ± 0.2 (11) | 4.1 ± 0.7 (5) | 2.5 ± 0.4 (9) |
| % collagen area | 3.1 ± 0.3 (4) | n.a. | 0.8 ± 0.2 (5) | 43.5 ± 4.4 (11) | 6.0 ± 3.0 (4) | 2.1 ± 1.2 (4) | n.a. | 62.9 ± 4.1 (5) |