Table 1.
S. No. | Conc mg/ml | % inhibition EtOAc | % inhibition MeOH |
1 | 10 | 7.04 ± 1.31 | 15.34 ± 1.34* |
2 | 20 | 12.85 ± 1.36 | 21.63 ± 1.39* |
3 | 30 | 16.45 ± 1.41 | 26.74 ± 1.42* |
4 | 40 | 22.12 ± 1.44 | 32.06 ± 1.45* |
5 | 50 | 27.42 ± 1.49 | 41.56 ± 1.51* |
6 | 60 | 30.41 ± 1.52 | 50.54 ± 1.62* |
7 | 70 | 36.21 ± 1.61 | 60.12 ± 1.68* |
8 | 80 | 43.95 ± 1.69 | 68.31 ± 1.72* |
9 | 90 | 46.42 ± 1.71 | 75.38 ± 1.73* |
10 | 100 | 49.36 ± 1.76 | 87.43 ± 1.79* |
Increasing concentration of ethyl acetate and methanol extracts of Chenopodium album (leaves) leads to decreased cell proliferation and enhanced cell toxicity on MCF-7 (breast adenocarcinoma estrogen receptor positive) cell line. Cells were seeded in tissue culture petri plates and treated with plant extracts. MeOH extract exhibited significant antiproliferative activity and showing maximum 87.43% inhibition against cell line MCF-7 at the concentration 100 mg/ml at 24 h. Results represent mean value of triplicate culture with SD. Students' unpaired t-test *p < 0.05 vs. ethyl acetate extract.