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. 2009 Jul-Aug;2(3):160–165. doi: 10.4161/oxim.2.3.8837

Table 1.

(A) TBE (trypan blue exclusion) bioassay

S. No. Conc mg/ml % inhibition EtOAc % inhibition MeOH
1 10 7.04 ± 1.31 15.34 ± 1.34*
2 20 12.85 ± 1.36 21.63 ± 1.39*
3 30 16.45 ± 1.41 26.74 ± 1.42*
4 40 22.12 ± 1.44 32.06 ± 1.45*
5 50 27.42 ± 1.49 41.56 ± 1.51*
6 60 30.41 ± 1.52 50.54 ± 1.62*
7 70 36.21 ± 1.61 60.12 ± 1.68*
8 80 43.95 ± 1.69 68.31 ± 1.72*
9 90 46.42 ± 1.71 75.38 ± 1.73*
10 100 49.36 ± 1.76 87.43 ± 1.79*

Increasing concentration of ethyl acetate and methanol extracts of Chenopodium album (leaves) leads to decreased cell proliferation and enhanced cell toxicity on MCF-7 (breast adenocarcinoma estrogen receptor positive) cell line. Cells were seeded in tissue culture petri plates and treated with plant extracts. MeOH extract exhibited significant antiproliferative activity and showing maximum 87.43% inhibition against cell line MCF-7 at the concentration 100 mg/ml at 24 h. Results represent mean value of triplicate culture with SD. Students' unpaired t-test *p < 0.05 vs. ethyl acetate extract.