Table 2.
S. No. | Conc mg/ml | % inhibition EtOAc | % inhibition MeOH |
1 | 10 | 3.45 ± 1.42 | 7.21 ± 1.44* |
2 | 20 | 5.98 ± 1.45 | 10.54 ± 1.45* |
3 | 30 | 10.23 ± 1.51 | 15.48 ± 1.56* |
4 | 40 | 12.23 ± 1.55 | 20.54 ± 1.61* |
5 | 50 | 15.65 ± 1.61 | 25.42 ± 1.69* |
6 | 60 | 19.32 ± 1.68 | 30.12 ± 1.70* |
7 | 70 | 22.67 ± 1.72 | 37.53 ± 1.76* |
8 | 80 | 25.43 ± 1.76 | 41.98 ± 1.82* |
9 | 90 | 26.09 ± 1.81 | 45.76 ± 1.88* |
10 | 100 | 27.54 ± 1.84 | 48.65 ± 1.92* |
Increasing concentration of ethyl acetate and methanol extracts of Chenopodium album (leaves) leads to decreased cell proliferation and enhanced cell toxicity on MDA-MB-468 (breast adenocarcinoma estrogen receptor negative) cell line. Cells were seeded in tissue culture Petri plates and treated with plant extracts. MeOH extract exhibited significant antiproliferative activity and showing maximum 48.65% inhibition against cell line MDA-MB-468 at the concentration 100 mg/ml at 24 h. Results represent mean value of triplicate culture with SD. Students' unpaired t-test *p < 0.05 vs. ethyl acetate extract