Table 3.
Intracellular ROS accumulation in cerebral and peripheral cells of anxious and non-anxious mice
Mean fluorescent intensity (arbitrary units) | ||
Type of cells | Anxious mice | Non-anxious mice |
Neurons of cerebral cortex | 1223 ± 232** | 177 ± 76 |
Neurons of cerebellum | 546 ± 128* | 227 ± 41 |
Neurons of hippocampus | 1749 ± 566* | 227 ± 51 |
Glial cells of cerebral cortex | 429 ± 48 | 310 ± 72 |
Glial cells of cerebellum | 343 ± 36* | 195 ± 31 |
Glial cells of hippocampus | 468 ± 43* | 319 ± 29 |
Lymphocytes | 251 ± 46* | 152 ± 11 |
Monocytes | 56 ± 9* | 35 ± 2.5 |
Granulocytes | 1979 ± 405** | 448 ± 77 |
The mean fluorescent intensity corresponds to fluorescence resulting from intracellular DCFH-DA oxidation by intracellular ROS. Data are expressed as mean ± SEM. (n = 10). *p < 0.05; **p < 0.01. (data published by Rammal et al.42 in Brain Behav Immun).