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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1471–1477. doi: 10.1161/ATVBAHA.109.191825

Table 2.

Hepatic C7H activity, protein, and mRNA and LDLR protein and selected mRNA of genes that modulate hepatic cholesterol levels (cholesterol efflux: ABCA1, ABCG8 and synthesis: HMG-CoA reductase and synthases) in control and CEE-treated monkeys (Mean ± SEM, n=17/group)

CTL CEE p-value
LDLR protein (AU) 6.57 (0.5) 7.64 (0.52) 0.15
C7H activity (pmol/min/mg) 1.17 (0.20) 2.48 (0.58) 0.23
C7H protein (AU) 3.48 (0.50) 6.50 (0.88) 0.005
C7H mRNA (AU) 35.86 (9.61) 61.24 (16.88) 0.22
ABCA1 mRNA (AU) 9.33 (0.62) 9.41 (0.75) 0.60
ABCG8 mRNA (AU) 142.38 (8.70) 151.23 (10.29) 0.52
HMG-CoA Reductase
mRNA 		(AU) 6.19 (0.69) 5.98 (0.47) 0.80
HMG-CoA Synthase
(cytoplasmic) mRNA 		(AU) 0.30 (0.06) 0.55 (0.11) 0.061
HMG-CoA Synthase
(mitochondrial) mRNA 		(AU) 1612.30 (176.32) 1709.16 (200.89) 0.72