Table 4.
Risk of endometrial cancer in relation to the use of other medications
N cases | N controls | Age and BMI adjusted OR*(95%CI) | |
---|---|---|---|
Pain and inflammation | |||
NSAIDs | P(trend duration) = 0.12 | ||
No | 373 | 353 | 1.0 (ref.) |
Yes | 96 | 114 | 0.7 (0.5–0.97) |
Aspirin | |||
No | 413 | 391 | 1.0 (ref.) |
Yes | 56 | 76 | 0.7 (0.4–1.0) |
Non-aspirin NSAIDs | |||
No | 429 | 429 | 1.0 (ref.) |
Yes | 40 | 38 | 0.8 (0.5–1.3) |
Analgesics | |||
No | 451 | 455 | 1.0 (ref.) |
Yes | 18 | 12 | 1.2 (0.5–2.7) |
Corticosteroids | |||
No | 447 | 450 | 1.0 (ref.) |
Yes | 22 | 17 | 1.1 (0.5–2.1) |
Mood disorders | |||
Serotonin selective reuptake inhibitors | |||
No | 421 | 423 | 1.0 (ref.) |
Yes | 48 | 44 | 0.9 (0.6–1.4) |
Benzodiazepines | |||
No | 445 | 441 | 1.0 (ref.) |
Yes | 24 | 26 | 0.9 (0.5–1.7) |
Gastrointestinal | |||
Proton pump inhibitors | |||
No | 442 | 436 | 1.0 (ref.) |
Yes | 27 | 31 | 0.7 (0.4–1.2) |
adjusted for age (linear spline) and BMI in 4 categories