Figure 1.
Percentage of patients with childhood-onset schizophrenia (COS) with rare copy number variations and/or chromosomal anomalies by prepsychotic developmental pattern. Patients with COS had varied developmental histories, and we assigned them to one of three basic categories: pervasive developmental disorder (PDD, 23 met criteria for PDD not otherwise specified, one for autism and one for Asperger's syndrome); developmental problems, for anyone who had documented difficulties in the areas of speech and language, motor delays, or social/peer relationship problems; and clean, for those who did not have any developmental delays or problems before onset of schizophrenia.