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. Author manuscript; available in PMC: 2009 Oct 19.
Published in final edited form as: Mol Carcinog. 2009 Jun;48(6):488–497. doi: 10.1002/mc.20485

Figure 2. MAPK mediates the downstream affect of EGF in A549 cells.

Figure 2

Western blot analysis of the EGFR, MAPK (p44/42), phosphorylated MAPK (P-p44/42), E-cadherin, and smad-2, in lysates of A549 cells treated with EGF (200 ng/mL) or EGF and PD98059 (50 µM). Seventy micrograms of protein was loaded per well. In EGF treated A549 cells, the increase in phosphorylated MAPK signal is reversed by pretreatment with PD98059.