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. Author manuscript; available in PMC: 2010 Sep 7.
Published in final edited form as: J Theor Biol. 2009 May 31;260(1):110–120. doi: 10.1016/j.jtbi.2009.05.018

Figure 7. Time course of entry into mitosis: effects of exogenous Cdc25 and unreplicated DNA.

Figure 7

In the experiments of Kumagai et al. (1998a) extracts were immunodepleted of endogenous Cdc25 and exogenous, recombinant Cdc25 was added back, either wild type (WT) or non-phosphorylable by Chk1 (S287A). The theoretical curves were computed from the full model (Table 2) and the final parameter set (Table 3).