Figure 4. Glandular function recovers after stopping poly(I:C) treatment.
Mice (n=5 per group) were either treated with poly(I:C) or PBS every other day for 2 weeks. Pilocarpine induced saliva was determined on days 16, and 40 (2 and 26 days after stopping treatment). Data are represented as mean±SEM saliva volume/body weight (μl/gm). Note that mean saliva volume in poly(I:C) treated mice was significantly lower than the PBS treated mice 2 days after stopping the treatment. However, on day 26 after stopping the treatment, the difference in mean saliva volume between the 2 groups of mice was not significant.