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Salivary fluid protein levels and the predictive power of each protein individually and in combination.
| A, Wilcoxon test for each salivary protein (mean ± SD) (ng/ml). | |||
|---|---|---|---|
| Healthy controls | Cancer patients | p-value | |
| VEGF | 2.1±1.2 | 3.7±1.6 | <0.0001 |
| EGF | 2.1±1.3 | 3.7±1.7 | <0.0001 |
| CEA | 66.1±27.1 | 83.0±31.0 | 0.0106 |
| B, ROC curve analysis on the logistic regression models. | |||
|---|---|---|---|
| AUC (%) | Sensitivity (%) | Specificity (%) | |
| VEGF | 80 | 74 | 73 |
| EGF | 77 | 78 | 68 |
| CEA | 65 | 70 | 56 |
| VEGF + EGF | 84 | 83 | 74 |
AUC, area under the curve.
