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. Author manuscript; available in PMC: 2010 Jul 31.
Published in final edited form as: J Mol Biol. 2009 Jun 6;390(5):913–923. doi: 10.1016/j.jmb.2009.06.007

Figure 1. Models for synaptotagmin 1.

Figure 1

(a) Synaptotagmin 1 is a membrane protein containing two C2 domains, which is anchored to the synaptic vesicle membrane by a single transmembrane helix. This model was built from models for the isolated C2A(PDB:1BYN) and C2B(PDB:1K5W) domains, which were connected with an unstructured linker using InsightII. (b) Crystal structure of the soluble fragment of synaptotagmin 1 (PDB:2R83). The C2A and C2B domains are shown in yellow and magenta.