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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Ann Thorac Surg. 2009 Oct;88(4):1162–1170. doi: 10.1016/j.athoracsur.2009.06.028

Table 4.

Associations of baseline characteristics at time of VAD implant and adverse event incidence: Hazard ratios (and 95% Confidence Intervals) from multivariate models (N = 195).a

Characteristic at VAD implantation
Adverse Event Type Gender (male) Age (>54) Implantation Era (before 2001) Intention to Treat (Bridge to Transplant) VAD Type (LVAD) Model Fit, χ2 (df=5)
Any AE 0.87
(0.61, 1.26)		 0.91
(0.66, 1.24)		 0.94
(0.67, 1.31)		 0.74
(0.48, 1.13)		 1.03
(0.75, 1.42)		 3.83
Arrhythmia 1.65
(0.82, 3.29)		 0.95
(0.58, 1.54)		 0.70
(0.42, 1.16)		 2.14
(0.96, 4.76)		 2.36**
(1.32, 4.21)		 16.45**
Tamponade 0.98
(0.50, 1.93)		 1.15
(0.66, 2.01)		 1.24
(0.70, 2.19)		 1.50
(0.62, 3.66)		 1.07
(0.60, 1.93)		 2.26
RV Failure 1.60
(0.60, 4.34)		 1.48
(0.70, 3.14)		 1.59
(0.68, 3.76)		 0.35*
(0.14, 0.89)		 ---b 6.36
Thromboembolism 0.51
(0.14, 1.81)		 3.26*
(1.09, 9.80)		 0.12*
(0.02, 0.91)		 0.69
(0.23, 2.04)		 1.99
(0.61, 6.55)		 14.47*
Respiratory 0.60
(0.31, 1.15)		 1.01
(0.55, 1.86)		 0.71
(0.36, 1.37)		 0.95
(0.44, 2.07)		 0.60
(0.33, 1.09)		 9.19
Neurologic 0.53
(0.27, 1.03)		 1.21
(0.66, 2.23)		 2.17*
(1.20, 3.93)		 2.62
(0.76, 8.85)		 1.28
(0.69, 2.39)		 16.07**
Renal 1.83
(0.66, 5.09)		 1.03
(0.47, 2.25)		 0.36
(0.12, 1.09)		 0.43
(0.18, 1.04)		 0.40*
(0.18, 0.89)		 15.34**
Hepatic 1.43
(0.42, 4.95)		 0.97
(0.35, 2.64)		 0.27
(0.06, 1.23)		 0.58
(0.19, 1.82)		 0.37
(0.13, 1.03)		 9.81
Bleeding 0.92
(0.56, 1.50)		 0.84
(0.54, 1.30)		 0.87
(0.55, 1.38)		 0.78
(0.45, 1.38)		 0.56**
(0.36, 0.85)		 11.79*
Infection 1.43
(0.81, 2.51)		 0.80
(0.50, 1.27)		 1.41
(0.87, 2.27)		 0.85
(0.44, 1.63)		 0.64
(0.41, 1.00)		 7.37
Reoperation 0.64
(0.36, 1.15)		 0.95
(0.56, 1.61)		 0.92
(0.52, 1.60)		 0.76
(0.39, 1.49)		 1.29
(0.74, 2.24)		 4.07
Device Malfunction 0.48
(0.16, 1.41)		 1.21
(0.47, 3.28)		 0.30
(0.09, 1.07)		 2.47
(0.54, 11.23)		 0.76
(0.29, 1.95)		 6.67
*

p<.05

**

p<.01

***

p<.001

a

Hazard ratios <1.00 indicate a reduced risk of an AE associated with a given characteristic. Hazard ratios >1 indicate increased risk. Time to each AE was regressed on the set of baseline characteristics.

b

VAD type could not be included as a predictor of RV failure because patients who received BiVADs had right ventricular support and thus could not develop new RV failure.