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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Clin Cancer Res. 2009 Jul 21;15(15):4993–5001. doi: 10.1158/1078-0432.CCR-08-2222

Table 3.

Summary of bivariate analysis showing the relationship between tumor volume and tumor grade with the significant perfusion/permeability estimators obtained with Gd-DTPA DCE-MRI. All of the post MRI image parameters were found to correlate with tumor volume. AUC t-max and washin correlated with tumor grade. Therefore it is not possible to determine whether these parameters are independent predictors of outcome.

Tumor Volume Tumor Grade


Spearman p -value Exact
Rank
sum test
T Test



Pre AUC60 −0.239 0.155 0.256 0.3


AUC90 −0.241 0.151 0.242 0.294


AUC t-max −0.208 0.216 0.124 0.182


Washin −0.175 0.3 0.756 0.787


Washout −0.293 0.079 0.141 0.189

Post AUC 60 0.500 0.041 0.506 0.379


AUC 90 0.515 0.035 0.646 0.346


AUC t-max 0.610 0.009 0.009 0.008


Washin 0.534 0.027 0.234 0.039


Washiout 0.586 0.014 0.328 0.189



HT(min) HT(min) 0.244 0.146 0.033 0.104

AUC 60 = area under the curve integrated up to 60 sec

AUC 90 = area under the curve integrated up to 90 sec

AUC t-max = area under the curve integrated up to time to muscle peak