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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Curr Opin Struct Biol. 2009 Jul 23;19(4):473–482. doi: 10.1016/j.sbi.2009.07.003

Figure 1.

Figure 1

The life-cycle of HIV-1. The virus attaches to its target cell and subsequent to membrane fusion the RNA of the virus is reverse transcribed to DNA which is integrated into the cell’s genome. During it’s virulent phase the viral DNA is transcribed back to RNA which codes for various proteins required for virion assembly. Drugs can inhibit various events in the life cycle. The focus of the review is peptides that inhibit fusion to the target cell. Figure from http://www.wiley.com/legacy/college/boyer/0470003790/cutting_edge/aids_therapies/hiv_lifecycle.gif