Skip to main content
. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Curr Opin Struct Biol. 2009 Jul 23;19(4):473–482. doi: 10.1016/j.sbi.2009.07.003

Figure 4.

Figure 4

X-ray structure of the gp41 6-helix bundle. The bundle was formed from synthetic N36 and C34 peptides (see Table 1). Panel A shows an end view of the 6-HB with the C-peptides in grey and the trimeric core in green. Panel B is a side view illustrating the trimeric N-core interacting with the C-peptides. The pocket binding domain (PDB; WMEWDREI) residues Trp, Trp and Ile of C34 are shown explicitly. These interact with the hydrophobic pocket of the N-trimeric core. The model was built using coordinates from the PDB 1AIK.