Table 1.
1 Week | 1 Week | |||
---|---|---|---|---|
CTRL n=8 |
EXP n=12 |
CTRL n=8 |
EXP n=12 |
|
MR, grade | 0.5 (0–2) | 3.0 (2–4)††† | 0.5 (0–1) | 3.0 (1–4)††† |
HR, min−1 | 105±15 | 109±11 | 103±14 | 106±18 |
Body weight, kg |
58±10 | 57±10 | 60±10 | 58±6 |
LV massI, g/m2 |
… | … | 173±17 | 201±18** |
LVEDVI, ml/m2 | 110±28 | 115±17 | 116±38 | 134±31‡ |
LVESVI, ml/m2 | 87±22 | 89±13 | 91±30 | 100±22 |
LVEF, % | 21±4 | 23±3 | 22±7 | 25±4 |
LVPmax, mmHg | 93±10 | 93±10 | 106±15 | 102±16 |
Group mean±SD and median (range). EDVI indicates end-diastolic volume index; EF, ejection fraction; ESVI, end-systolic volume index; HR, heart rate; LV, left ventricular; massI, mass index; MR, mitral regurgitation; Pmax, maximum systolic pressure.
P<0.01 vs CTRL by t test for unpaired observations.
P<0.001 vs CTRL using generalized Fisher’s exact test.
P=0.015 vs 1 week, using 2-way repeated measures ANOVA with the Bonferroni correction (level of significance adjusted to P<0.05/3).