Table 2.

Change in BNP, PRSW, and Tau From 1 to 12 Weeks

	CTRL (n=8)			EXP (n=12)
	1 Week	12 Weeks	Δ	1 Week	12 Weeks	Δ
BNP, pmol/L	6.7±3.8	3.7±1.5	−3.0±3.6	7.9±4.4	3.4±1.1**	−4.5±4.4
PRSW, mm Hg	48±7	71±16***	23±18	54±11	62±11	9±13
Tau, ms	35±10	31±7	−4±7	37±6	33±10	−3±11

Group mean±SD. Δ indicates change from 1 to 12 weeks; BNP, B-type natriuretic peptide; PRSW, preload recruitable stroke work; tau, LV relaxation time constant. Difference in change was analyzed by t test for unpaired observations.

^**P<0.01 and

^***P<0.001 vs 1 week, using 2-way repeated measures ANOVA with the Bonferroni correction (level of significance adjusted to P<0.05/3).