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. Author manuscript; available in PMC: 2010 Aug 28.
Published in final edited form as: Chem Biol. 2009 Aug 28;16(8):893–906. doi: 10.1016/j.chembiol.2009.06.012

Figure 4.

Figure 4

Deltamethrin (0.1 μM) and PbTx-3 (5 nM) enhance hoiamide A-induced elevation of neuronal [Na+]i. (A) Time-response relationships for hoiamide A-induced elevation of neuronal [Na+]i ; (B) Time-response relationships for hoiamide A-induced elevation of neuronal [Na+]i in the presence of 5 nM PbTx-3; (C) Time-response relationships for hoiamide A-induced elevation of neuronal [Na+]i in the presence of 0.1 μM deltamethrin; (D) Nonlinear regression analysis of the SBFI response [area under the curve (AUC)] versus the concentration of hoiamide A in the presence and absence of 5 nM PbTx-3; (E) Nonlinear regression analysis of the SBFI response [area under the curve (AUC)] versus the concentration of hoiamide A in the presence and absence of 0.1 μM deltamethrin. Each data point represents the Mean ± S.E.M. from two experiments performed in triplicate.