Table 2. The CKD-EPI Equation for Estimating GFR on the Natural Scale*.
Race and Sex | Serum Creatinine μmol/L (mg/dL) | Equation |
---|---|---|
Black | ||
Female | ≤62 (≤0.7) | GFR = 166 × (Scr/0.7)-0.329 × (0.993)Age |
>62 (>0.7) | GFR = 166 × (Scr/0.7)-1.209 × (0.993)Age | |
Male | ≤80 (≤0.9) | GFR = 163 × (Scr/0.9)-0.411 × (0.993)Age |
>80 (>0.9) | GFR = 163 × (Scr/0.9)-1.209 × (0.993)Age | |
White or other | ||
Female | ≤62 (≤0.7) | GFR = 144 × (Scr/0.7)-0.329 × (0.993)Age |
>62 (>0.7) | GFR = 144 × (Scr/0.7)-1.209 × (0.993)Age | |
Male | ≤80 (≤0.9) | GFR = 141 × (Scr/0.9)-0.411 × (0.993)Age |
>80 (>0.9) | GFR = 141 × (Scr/0.9)-1.209 × (0.993)Age |
CKD-EPI = Chronic Kidney Disease Epidemiology Collaboration; GFR = glomerular filtration rate.
Expressed for specified race, sex, and serum creatinine level. To convert GFR from mL/min per 1.73 m2 to mL/s per 1.73 m2, multiply by 0.0167. We derived equation coefficients from pooled development and internal validation data sets.
The CKD-EPI equation, expressed as a single equation, is GFR = 141 × min(Scr/κ, 1)α × max(Scr/κ, 1)-1.209 × 0.993Age × 1.018 [if female] _ 1.159 [if black], where Scr is serum creatinine, κ is 0.7 for females and 0.9 for males, α is -0.329 for females and -0.411 for males, min indicates the minimum of Scr/κor 1, and max indicates the maximum of Scr/κ or 1. In this table, the multiplication factors for race and sex are incorporated into the intercept, which results in different intercepts for age and sex combinations.