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. Author manuscript; available in PMC: 2009 Oct 19.
Published in final edited form as: Ann Intern Med. 2009 May 5;150(9):604–612. doi: 10.7326/0003-4819-150-9-200905050-00006

Table 4. Comparison of the CKD-EPI and MDRD Study Equations in Estimating GFR Stage and Comparison With Measured GFR in the Validation Data Set*.

CKD-EPI-Estimated GFR and Measured GFR MDRD Study–Estimated GFR, n (%) Total Patients, n (%)
>90 mL/min per 1.73 m2 60–89 mL/min per 1.73 m2 30–59 mL/min per 1.73 m2 15–29 mL/min per 1.73 m2 <15 mL/min per 1.73 m2
Estimated GFR >90 mL/minper 1.73 m2 670 (17.2) 319 (8.2) 0 0 0 989 (25.4)
Measured GFR
 >90 mL/min per 1.73 m2 586 (15.0) 221 (5.7) 93 (2.4)
 60-89 mL/min per 1.73 m2 75 (1.9) 4 (0.1)
 30-59 mL/min per 1.73 m2 9 (0.3) 1 (0.0)
 15-29 mL/min per 1.73 m2 0 0
 <15 mL/min per 1.73 m2 0
Estimated GFR 60-89 mL/min per 1.73 m2 2 (0.0) 803 (20.6) 190 (4.9) 0 0 995 (25.5)
Measured GFR
 >90 mL/min per 1.73 m2 0 263 (6.8) 11(0.3)
 60-89 mL/min per 1.73 m2 1 (0.01) 459 (11.8) 110 (2.8)
 30-59 mL/min per 1.73 m2 1 (0.0) 77 (2.0) 69 (1.8)
 15-29 mL/min per 1.73 m2 0 4 (0.1) 0
<15 mL/min per 1.73 m2<15 0 0 0
Estimated GFR 30-59 mL/min per 1.73 m2 2 (0.0) 1251 (32.1) 42 (1.1) 0 1295 (33.2)
Measured GFR
 >90 mL/min per 1.73 m2 0 118 (3.0) 0
 60-89 mL/min per 1.73 m2 2 (0.0) 221 (5.7) 0
 30-59 mL/min per 1.73 m2 0 903 (23.7) 20 (0.5)
 15-29 mL/min per 1.73 m2 0 105 (2.7) 21 (0.5)
<15 mL/min per 1.73 m2 0 4 (0.1) 0
Estimated GFR 15-29 mL/min per 1.73 m2 0 0 9 (0.2) 462 (11.9) 2 (0.0) 473 (12.1)
Measured GFR
 >90 mL/min per 1.73 m2 0 0 0
 60-89 mL/min per 1.73 m2 0 0 0
 30-59 mL/min per 1.73 m2 5 (0.1) 109 (2.8) 1 (0.0)
 15-29 mL/min per 1.73 m2 4 (0.1) 302 (7.8) 1 (0.0)
<15 mL/min per 1.73 m2 0 51 (1.3) 0
Estimated GFR <15 mL/min per 1.73 m2 0 0 0 5 (0.1) 139 (3.6) 144 (3.7)
Measured GFR
 >90 mL/min per 1.73 m2 0 0
 60-89 mL/min per 1.73 m2 0 2 (0.0)
 30-59 mL/min per 1.73 m2 0 0
 15-29 mL/min per 1.73 m2 2 (0.0) 32 (0.8)
 <15 mL/min per 1.73 m2 3 (0.1) 105 (2.7)
Total 672 (17.3) 1124 (28.9) 1450 (37.2) 509 (13.1) 141 (3.6) 3896 (100)

CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; MDRD, Modification of Diet in Renal Disease. Values in each cell represent number and percent (in parenthesis). Values in small italics represent subjects with measured GFR. Cell percents may not total to margin percents because of rounding. Shaded cells represent agreement. Cells above the shaded diagonal cells represent disagreement, with higher estimated GFR categories using the CKD-EPI equation. Cells below the shaded diagonal cells represent disagreement, with lower estimated GFR categories using the CKD-EPI equation. Units for GFR in ml/min/1.73 m2. To convert GFR from mL/min/1.73 m2 to mL/s/1.73 m2, multiply by 0.0167.