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. Author manuscript; available in PMC: 2010 Jul 31.
Published in final edited form as: Mol Cell. 2009 Jul 31;35(2):247–253. doi: 10.1016/j.molcel.2009.06.035

Figure 3. Extended protein occupancy domains (EPODs).

Figure 3

Protein occupancy and RNA expression profiles are shown for early exponential phase growth, smoothed by averaging within a moving window of 512 base pairs. At the bottom, open reading frames (ORFs) are annotated on both strands. Automatically detected transcriptionally-silent EPODs are shown at the top. (A) A high protein occupancy and high RNA expression domain encompassing a region with genes encoding ribosomal protein subunits. (B) An EPOD automatically detected within a transcriptionally-silent region with genes encoding LPS biosynthesis products. A neighboring region encoding 50S ribosomal protein subunits (rpmG and rpmB) shows an equal level of protein occupancy but shows a high level of RNA expression. (C,D) Transcriptionally-silent EPODs detected within genes of unknown function encoding a predicted protein, yccE (C) and a conserved inner membrane protein, yliE (D).