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. Author manuscript; available in PMC: 2009 Oct 19.
Published in final edited form as: Vis Neurosci. 2009 Mar 11;26(2):177–187. doi: 10.1017/S0952523809090026

Table 1. The summary and comparison of the T-type Ca2+ current properties between the three subgroups of T-rich cone bipolar cells (CBCs) and the three T-type Ca2+ channel subunits.

The data for the DTT modulation are presented as the percentage of increase (+) or decrease (-) compared to control after the application of 2 mM DTT. The data for Ba2+/Ca2+ permeability are presented as the percentage of the Ba2+ current normalized to the Ca2+ current when 10 mM extracellular Ca2+ was replaced by 10 mM Ba2+. The data for Ba2+/Ca2+ permeability are presented as the percentage of the Ba2+ current normalized to the Ca2+ current when 10 mM extracellular Ca2+ was replaced by 10 mM Ba2+. The data for the Ni2+ sensitivity are presented as the percentage of the blockade after the application of 20 μM Ni2+. All data are presented as mean ± SD from the indicated number of cells.

CBC Subgroup 1 (n = 44) α1G (n = 10) CBC Subgroup 2 (n = 29) α 1H (n = 12) CBC Subgroup 3 (n = 20) α1I (n = 9)
DTT modulation -4.2 ±1.9 2.6 ± 2.7 32.2 ± 8.2 22 ± 5.2 -3.4 ± 1.7 4.0 ± 1.7
Ba2+/Ca2+ permeability 75.5 ± 6.7 82 ± 4.7 145 ± 11 146 ± 11 99 ± 0.9 99 ± 0.5
Ni2+ sensitivity -25.6 ± 6.0 -25.0 ± 6.0 -64 ± 11 -65 ± 15 -22 ± 8.0 -12 ± 8.0
Time to peak (ms) 19.5 ± 2.1 17.2 ± 2.2 24.7 ± 3.3 23.3 ± 2.4 34.8 ± 3.7 36.1 ± 3.1
Decay time (ms) 55.6 ± 3.8 31.6 ± 3.6 67.2 ± 6.2 35 ± 4.8 93.5 ± 5.8 75.4 ± 5.9