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Thermal stability of the p53tet mutants plotted as the fraction of unfolded protein vs. temperature at a total protein concentration of 100 μM (monomer). (A) Mutations at site 340 (WT, □; Lys, ▿; Gln, ◊; Ser, ○; His, ■; Glu, ●; Asp, ▴); (B) mutations at site 344 (Ala, ▿; Arg, ●; Gln, ⧫; Lys, □).
