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. 2009 Oct;297(4):G716–G725. doi: 10.1152/ajpgi.00194.2009

Fig. 1.

Fig. 1.

A and B: in vitro effects of vasoactive intestinal peptide (VIP) and TNF-α on the expression of l-type Ca2+ channel α1C subunit and contractility in human colonic circular smooth muscle strips. C: effects of incubation of primary cultures of human colonic circular smooth muscle cells (HCCSMCs) transfected with the hα1C1b promoter-luciferase gene construct with 10−7 M VIP and 20 ng/ml TNF-α. N = 3 or 4 independent experiments, *P < 0.05 vs. control (Ctr). AUC, area under contractions.