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Representative tracing of contractile activity of colonic circular muscle strips isolated from rats administered with saline (Ctr.), TNBS 65 mg/kg (TNBS 65), VIP + TNBS 65 mg/kg, TNBS 17 mg/kg (TNBS 17), and VPAC1/2 receptor antagonist (VPAC1/2 R) + TNBS 17 mg/kg for 7 days by an osmotic pump. All strips were cut into 10-mm-long and 3-mm-wide strips. The dry weight of each muscle strip is indicated in parenthesis.
