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. 2009 Oct;297(4):G716–G725. doi: 10.1152/ajpgi.00194.2009

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Fig. 6. — A: decrease in the muscularis externa concentration of VIP by inflammation induced with 68-mg/kg dose of TNBS (TNBS68) was significantly greater than that induced with the 17-mg/kg dose (TNBS17) on postinflammation day 7. N = 3 rats for each group. *P < 0.05 vs. control; #P < 0.05 vs. TNBS68 group. B: 68-mg/kg dose of TNBS reduced the muscularis externa (ME) concentration of VIP by day 1 postinflammation, and it remained at the reduced level at least until day 7. C: serum VIP concentration on day 7 of TNBS68 inflammation was also significantly lower than that in controls. However, the infusion of exogenous VIP by an osmotic pump significantly elevated the serum VIP concentration that was sustained on day 7 of inflammation. Rats infused with an identical daily volume of saline by an osmotic pump served as controls. N = 4 rats for each group. *P < 0.05 vs. control, P < 0.05 vs. TNBS68 group.