Table 4.
Changes in the degree of liver fibrosis, inflammation, and collagen content before and after AT1 receptor blockade with losartan
Before Treatment | After Treatment | P | |
---|---|---|---|
METAVIR | |||
Fibrosis | 2.71±0.83 | 2.57±0.94 | ns |
Activity score | 2.29±1.14 | 1.57±0.94 | <0.05 |
Piecemeal | 1.64±0.75 | 1.07±0.61 | <0.05 |
Lobular | 0.64±0.63 | 0.50±0.52 | ns |
Morphometric analysis | |||
Sirius red positive area, % | 5.86±1.65 | 5.90±2.17 | ns |
Values are means ± SD.