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The effect of heat acclimation on pilocarpine-induced sweat rate. The responses of male subjects (n = 3) are indicated by the solid circles with long-dashed lines; female subjects (n = 5) are indicated by the open circles and short-dashed lines; the combined mean response is indicated by the solid squares and solid line. There was an 18% increase of the sweat gland capacity in the control arm (P = 0.021) and a 52% decrease in the BOTOX-treated forearm (P < 0.001).
