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. 2009 Aug 5;297(4):R1095–R1102. doi: 10.1152/ajpregu.90902.2008

Fig. 3.

Fig. 3.

Respiratory control and ADP-to-O ratios. The ADP-to-O ratio is an index of the coupling of oxygen consumption to oxidative phosphorylation. Endotoxin reduced the respiratory control ratio (RCR) (P < 0.001, for comparison of the control to the endotoxin group) but did not change the ADP-to-O ratio. Administration of MitoQ prevented this endotoxin-induced reduction in RCR (P < 0.01 for comparison of endotoxin to the endotoxin + MitoQ group). *Statistically significant difference from the other groups.