Fig. 4.

Mitochondrial metabolic function in adipose tissue is correlated with insulin sensitivity. Schematics of mitochondrial metabolic pathways highlighting genes whose adipose tissue expression (before and after TZD treatment) was positively correlated with R_d. (A) β-oxidation of fatty acids, TCA cycle, and branched chain amino acid degradation. (B) Oxidative phosphorylation. Dark orange ovals – genes with expression vs. R_d correlations of r > 0.5. Light orange ovals – genes with expression vs. R_d correlations of r = 0.45–0.50.