TABLE 1. Serum parameters in DIO mice, 36hr. after CLD liposome administration.

	PBS liposomes	CLD liposomes
PAI-1	3.5 ng/ml ±0.52	4.7 ng/ml ±1.12	p = 0.345
MCP-1	17.3 pg/ml ±1.87	46.6 pg/ml ±7.78	p = 0.002
Leptin	8.2 ng/ml ±1.23	11.1 ng/ml ±1.70	p = 0.192
Resistin	2.0 ng/ml ±0.34	1.9 ng/ml ±0.44	p = 0.922
IL-6	13.8 pg/ml ±2.68	19.2 pg/ml ±11.27	p = 0.657
IL-10	17.1 pg/ml ±2.41	14.4 pg/ml ±4.82	p = 0.607
Triglyceride	117.2 mg/dl ±10.4	124.3 mg/dl ±8.6	p = 0.631
Cholesterol	148 mg/dl ±6.3	174.3 mg/dl ±4.1	p = 0.014
Fasted glucose	130 mg/dl ± 16	172 mg/dl ± 21	p = 0.126
Fasted insulin	0.28 ng/ml ± 0.07	0.76 ng/ml ± 0.3	p = 0.004

Plasminogen activator inhibitor 1 (PAI-1), monocyte chemoattractant protein (MCP-1), leptin, and resistin were measured in serum using Bio-plex™ technology (Bio-Rad). IL-6 and IL-10 were measured using Luminex® Beadlyte® technology (Upstate). All values are the mean ±S.E. of n ≥6. Triglyceride and cholesterol values are the mean ±S.E. of n ≥4. Fasted glucose and insulin values are the mean ±S.E. of n ≥5.