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. Author manuscript; available in PMC: 2010 Nov 2.
Published in final edited form as: DNA Repair (Amst). 2009 Aug 26;8(11):1258–1263. doi: 10.1016/j.dnarep.2009.07.009

Table 1.

Sensitivity to ionizing radiation after pretreatment with hydroxyurea and aphidicolin at different stages of the cell cycle.

A (G1) AA8 irs1SF V79 V-C8 K1 Xrs6 XR-1 Xrs6 compl
HU (200μM) 0.93 (0.06) 0.94 (0.10) 0.83 (0.04) 1.16 (0.06) 0.93 (0.04) 0.75 (0.13) 0.57 (0.11) 0.88 (0.08)
APH (1μg/ml) 0.99 (0.06) 0.85 (0.15) 0.76 (0.04) 0.85 (0.04) 0.93 (0.04) 0.83 (0.15) 0.60 (0.09) 0.91 (0.05)
IR (1Gy) 0.64 (0.05) 0.51 (0.04) 0.85 (0.04) 0.66 (0.04) 0.74 (0.05) 0.027 (0.008) 0.081 (0.010) 0.71 (0.06)
HU&IR 0.54 (0.02) 0.53 (0.06) 0.66 (0.04) 0.71 (0.02) 0.63 (0.04) 0.0051 (0.0015) 0.0137 (0.0058) 0.57 (0.03)
APH&IR 0.35 (0.04) 0.37 (0.01) 0.53 (0.03) 0.70 (0.04) 0.53 (0.04) 0.0031 (0.0008) 0.0116 (0.0084) 0.61 (0.02)
B (S) AA8 irs1SF K1 Xrs6
HU (200μM) 0.36 (0.04) 0.38 (0.06) 0.54 (0.05) 0.28 (0.06)
IR (1Gy) 0.76 (0.04) 0.46 (0.05) 0.85 (0.02) 0.0364 (0.0041)
HU&IR 0.12 (0.02) 0.12 (0.02) 0.35 (0.02) 0.0019 (0.0007)