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Cytotoxicity assessment of compounds against HeLa cells in a 3-day exposure
| Compound | CC50 (μg/ml) with HeLa cells | B. anthracis Ames with MIC (μg/ml) of: | Selectivity index (CC50/MIC)a |
|---|---|---|---|
| MBX 1066 | 33 | 0.3 | 110 |
| MBX 1090 | 10 | 0.6 | 17 |
| MBX 1113 | 3 | 1.1 | 2.7 |
| MBX 1128 | 17 | 1.4 | 12 |
CC50 values are divided by MICs for B. anthracis Ames in order to determine the selectivity index.
