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Bivariate analysis (Kaplan-Meier curves and log rank tests) for survival time. Survival of treated mice was monitored for 21 days (inoculation at day 0). The antimalarial treatment and route were as follows: chloroquine (CQ) (1, 5, or 10 mg/kg/day for 4 days); simalikalactone E (SKE) (0.5, 1, 5, 10, or 20 mg/kg/day); PO, oral route; IP, intraperitoneal route. When the line does not reach 0, the mice were still alive at day 21.
