TABLE 2.
Log bacterial concentrations over time in strains 4861a, 3126a, and 3131a incubated with various concentrations of TMP-SMX relative to the strain MICa
| TMP-SMX concn | Bacterial concn (CFU/ml)
|
|||
|---|---|---|---|---|
| Baseline | 4 h | 8 h | 24 h | |
| Control | 6.01 ± 0.047 | 7.55 ± 0.32 | 8.48 ± 0.47 | 10.07 ± 0.84 |
| 1× MIC | 6.08 ± 0.066 | 5.76 ± 0.39 | 6.57 ± 0.59 | 7.33 ± 1.09 |
| 4× MIC | 6.04 ± 0.11 | 5.29 ± 0.43 | 5.20 ± 0.88 | 5.24 ± 1.76 |
| 6× MIC | 6.03 ± 0.046 | 5.12 ± 0.42 | 5.23 ± 0.51 | 4.57 ± 1.72 |
| 10× MIC | 6.08 ± 0.084 | 3.62 ± 0.20 | 3.66 ± 0.037 | 3.30 ± 1.16 |
a
Results represent geometric mean and standard deviation of bacterial concentrations of the three strains in studies performed in duplicate.