TABLE 3.
Effects of antibiotic therapy on the clearance of Ab11 and Ab51 strains from mouse lungs, the frequency of sterile blood cultures, and mortality
| Treatment group (n) | Ab11
|
Ab51
|
||||
|---|---|---|---|---|---|---|
| Bacterial load (mean log10 CFU/g of lung ± SD) | % Sterile blood cultures | % Mortality | Bacterial load (mean log10 CFU/g of lung ± SD) | % Sterile blood cultures | % Mortality | |
| Control (15) | 8.28 ± 1.40 | 26.7 | 40 | 7.75 ± 1.07 | 20 | 93.3 |
| IPM (15) | 5.81 ± 1.13a | 80a | 53.3 | 5.46 ± 1.55a | 100a | 40a |
| CLA (15) | 6.50 ± 0.81a | 60 | 26.7 | 5.33 ± 1.88a | 93.3a | 33.3a |
a
P < 0.01 relative to the control group (by ANOVA, post hoc Tukey and Dunnett tests, and chi-square tests).