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. 2009 Aug 10;53(10):4305–4310. doi: 10.1128/AAC.00444-09

FIG. 1.

FIG. 1.

Twenty-four-hour time-kill curves, using AMP alone or in combination with CRO against clinical strains of E. faecalis in exponential growth phase. The AMP-CRO combination results are shown using 5 mg/liter CRO. Case 3: AMP alone was bactericidal using concentrations of 1 to 8 mg/liter; higher concentrations were less active. The AMP-CRO combination was synergistic for AMP concentrations using 0.12 to 0.5 mg/liter, extending the bactericidal effect to AMP concentrations of between 0.12 and 8 mg/liter. Case 4: AMP alone was bactericidal using concentrations of 0.5 to 8 mg/liter. The AMP-CRO combination was synergistic for AMP concentrations of 0.12 to 0.25 mg/liter, extending the bactericidal effect to AMP concentrations of between 0.12 and 8 mg/liter.