TABLE 4.
Effect of ciprofloxacin on viable organisms in bladders of mice infected with the four E. coli strains used in the study
| E. coli strain (plasmid) | Results (log CFU/g of bladder ± SD [no. of mice]) for mice treated with:
|
||
|---|---|---|---|
| Start-of-treatment control | End-of-treatment control | Ciprofloxacin | |
| CFT703-RR | 6.2 ± 1.1 (19) | 5.5 ± 1.3 (17) | 4.2 ± 0.5 (15)a |
| CFT703-RR Tc (pQnrA1) | 5.1 ± 0.8 (16) | 4.7 ± 0.5 (15) | 4.7 ± 0.3 (20)b |
| CFT703-RR Tc (pQnrS1) | 6.6 ± 1.5 (15) | 5.0 ± 0.9 (15) | 5.0 ± 0.9 (16)b |
| CFT703-RR-gyrA | 5.4 ± 0.8 (15) | 5.4 ± 0.8 (15) | 5.4 ± 0.7 (16)b |
a
P was 0.003 compared with the end-of-treatment control group.
b
P was >0.6 compared with the end-of-treatment control group.