Table 1.

Distribution of TP53 genotypes among CIN3+ cases versus women with persistent HPV infection and corresponding odds ratios and 95% confidence intervals, adjusted for age.

TP53 Polymorphism	Genotype	CIN3+ Cases (N=465)	Persistent HPV Controls (N=379)	OR*	95% CI*		p-trend
rs17887200†	AA	397	334	1.0			0.23
22369bp 3' of STP A>G	AG	58	43	1.2	0.78	1.9
	GG	2	0	NA
rs9894946†	CC	396	316	1.0			0.28
22342bp 3' of STP T>C	CT	59	60	0.76	0.51	1.1
	TT	4	3	1.2	0.25	5.6
rs1614984†	CC	249	221	1.0			0.18
21226bp 3' of STP C>T	CT	175	131	1.2	0.90	1.6
	TT	38	27	1.3	0.74	2.2
rs12951053†	TT	321	260	1.0			0.69
IVS7+92 T>G	GT	133	105	1.1	0.78	1.5
	GG	7	12	0.49	0.19	1.3
rs12947788†	CC	321	262	1.0			0.68
IVS7+72 T>C	CT	137	106	1.1	0.79	1.5
	TT	4	11	0.34	0.11	1.1
rs1625895†	GG	348	282	1.0			0.88
IVS6+62 A>G	AG	104	90	0.96	0.69	1.3
	AA	10	7	1.1	0.39	2.9
rs2909430†	AA	366	292	1.0			0.42
IVS4−91 A>G	AG	85	81	0.84	0.59	1.2
	GG	7	5	1.0	0.31	3.4
rs9895829†	TT	416	333	1.0			0.60
IVS4−125 T>C	CT	30	25	0.98	0.56	1.7
	CC	2	3	NA
rs1042522 (Pro72Arg)†	GG	206	182	1.0			0.29
Ex4+119 C>G	CG	191	144	1.2	0.91	1.7
	CC	61	50	1.2	0.75	1.8
rs1642785†	GG	217	166	1.0			0.66
IVS2+38 C>G	CG	190	167	0.88	0.65	1.2
	CC	51	43	0.99	0.62	1.6
rs8079544	GG	433	355	1.0			0.67
IVS1−112 G>A	AG	30	23	1.1	0.61	1.9
	AA	2	1	NA

^*OR, odds ratio. CI, confidence interval. Adjusted for age.

^†Numbers do not add up to totals because of missing values.