Table 2.

Risk estimates (odds ratios) and 95% confidence intervals for TP53 polymorphisms in CIN3+/persistent HPV cases compared to random controls, adjusted for age.

TP53 Polymorphism	Genotype	CIN3+/Persistent HPV Cases (N=844)	Population Controls (N=436)	OR*	95% CI*		p-trend
rs17887200†	AA	731	385	1.0			0.52
22369bp 3' of STP A>G	AG	101	45	1.2	0.82	1.7
	GG	2	2	0.55	0.08	3.9
rs9894946†	CC	712	366	1.0			0.82
22342bp 3' of STP T>C	CT	119	68	0.91	0.65	1.3
	TT	7	2	1.9	0.38	9.0
rs1614984†	CC	470	244	1.0			0.99
21226bp 3' of STP C>T	CT	306	152	1.1	0.82	1.3
	TT	65	36	0.93	0.60	1.4
rs12951053†	TT	581	323	1.0			0.05
IVS7+92 T>G	GT	238	101	1.3	1.0	1.7
	GG	19	8	1.3	0.58	3.1
rs12947788†	CC	583	324	1.0			0.09
IVS7+72 T>C	CT	243	104	1.3	1.0	1.7
	TT	15	8	1.1	0.45	2.6
rs1625895†	GG	630	332	1.0			0.18
IVS6+62 A>G	AG	194	97	1.1	0.80	1.4
	AA	17	2	4.4	1.0	19.0
rs2909430†	AA	658	345	1.0			0.34
IVS4−91 A>G	AG	166	86	1.0	0.76	1.4
	GG	12	1	6.1	0.79	47.5
rs9895829†	TT	749	379	1.0			0.98
IVS4−125 T>C	CT	55	31	0.89	0.57	1.4
	CC	5	1	2.5	0.29	21.4
rs1042522 (Pro72Arg)b	GG	388	234	1.0			0.002
Ex4+119 C>G	CG	335	160	1.3	0.99	1.6
	CC	111	37	1.8	1.2	2.7
rs1642785†	GG	383	213	1.0			0.04
IVS2+38 C>G	CG	357	183	1.1	0.85	1.4
	CC	94	31	1.7	1.1	2.6
rs8079544†	GG	788	404	1.0			0.70
IVS1−112 G>A	AG	53	29	0.93	0.58	1.5
	AA	3	2	0.77	0.13	4.6

^*OR, odds ratio. CI, confidence interval. Adjusted for age.

^†Numbers do not add up to totals because of missing values.