Table 3.
Early neonatal morbidity and mortality according to maternal intrapartum antibiotic receipt (non-ITT analysis; actual receipt of antibiotics analysis).
| Outcome | Category | Maternal Receipt of Intrapartum Antibiotics (N=1033) | No Maternal Receipt of Intrapartum Antibiotics (N=1380) | Odds ratio [95% CI] | P-value | ||
|---|---|---|---|---|---|---|---|
| n/N | % | n/N | % | ||||
| Infant illness at birth | Yes | 115/1031 | 11.2 | 118/1375 | 8.6 | 1.3 [1.0 – 1.8] | 0.03 |
| Admission to SCBUa | Yes | 117/925 | 12.6 | 116/1181 | 9.8 | 1.4 [1.1 – 1.9] | 0.04 |
| Early neonatal infection | Yes | 104/1033 | 10.1 | 137/1380 | 9.9 | 1.0 [0.8 – 1.3] | 0.91 |
| Duration of SCBU stay (days)b | Mean | 5.3 | - | - | 6 | 0.80c | 0.80c |
| Early neonatal death | Yes | 37/1033 | 3.6 | 47/1380 | 3.4 | 1.1 [0.7 – 1.6] | 0.82 |
| Dead | 30/116 | 25.9 | 25/115 | 21.7 | |||
| Vital status at discharge from SCBUb | Alive and unwell | 9/116 | 7.8 | 5/115 | 4.3 | 0.37 | |
| Alive and well | 77/116 | 66.4 | 85/115 | 73.9 | |||
| Deaths due to infectious causes | Yes | 8/37 | 21.6 | 5/47 | 10.6 | 0.23 | |
| Neonatal infections with unknown HIV statusd | Yes | 3/54 | 5.6 | 0/93 | 0 | 0.02 | |
a
SCBU= Special Care Baby Unit
b
Among those admitted to SCBU
c
Wilcoxon test
d
Neonatal infections and neonatal deaths by infant’s birth HIV status among HIV exposed infants only