Table 4.

Characteristics of mothers and infants, and early neonatal morbidity and mortality, according to maternal intrapartum antibiotic receipt and, if receipt, type of antibiotics (non-ITT analysis, detailed analysis).

Characteristic or Outcome	Category	Maternal Receipt of Intrapartum Antibiotics						P- value
		Yes: Study Antibiotics (N=866)		Yes: Non-Study Antibiotics (N=167)		No Antibiotics (N=1380)
MOTHER		n/N	%	n/N	%	n/N	%
HIV infection Status	Yes	735/855	86	149/165	90.3	1169/1364	85.7
PROM > 4 hours	Yes	167/825	20.2	50/158	31.6	222/1293	17.2	<0.0001
Clinical chorioaminionitis	Yes	2/162	0.3	2/151	1.3	1/1171	0.2	0.04
Histological chorioamnionitis	Yes	260/725	35.9	53/136	40.4	386/1119	34.5	0.37
INFANT
Birth weight (g)	Mean	2958		2734		2964		<0.0001
Ballard Score	Mean	38.1		37.1		38.6		<0.0001
Mean Apgar Score	1 minute	8.2		7.8		8.3		0.002
	5 minute	9.6		9.3		9.6		0.07
Infant illness at birth	Yes	82/864	9.5	33/167	19.8	118/1375	8.6	<0.0001
INFANT OUTCOMES
Admission to SCBU	Yes	80/773	10.3	37/152	24.3	116/1181	9.8	<0.0001
Early neonatal infection	Yes	90/866	10.4	14/167	8.4	137/1375	9.9	0.73
Early neonatal death	Yes	23/866	2.7	14/167	8.4	47/1380	3.4	0.001
Vital status at discharge from SCBU	Dead	20/80	25	10/36	27.8	25/115	21.7	0.71
	Alive & unwell	6/80	7.5	3/36	8.3	5/115	4.3
	Alive & well	54/80	67.5	23/36	63.9	85/115	73.9
Deaths due to infectious causes	Yes	6/23	26.1	2/14	14.3	5/47	10.6	0.27
Neonatal infection with respect to HIV statusa	Unknown	2/4	4.9	1/3	7.7	0/93	0	0.06
	Negative	80/656	12.2	10/124	8.1	107/987	10.8	0.37
	Positive	4/47	8.5	2/14	14.3	13/103	12.6	0.73
Neonatal death with respect to HIV statusa	Unknown	11/41	26.8	8/13	61.5	30/93	32.3	0.06
	Negative	10/656	1.5	4/124	3.2	9/987	0.9	0.08
	Positive	0/47	0	0/14	0	4/103	3.9	0.30

^aNeonatal infections and neonatal deaths by infant’s birth HIV status among HIV exposed infants only