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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: J Immunol. 2009 Mar 1;182(5):3278–3284. doi: 10.4049/jimmunol.0803417

FIGURE 1.

FIGURE 1

IFN-γ determines organ damage in Tgfb1−/− mice. A, Damage is Ifng dependent. Mice of the indicated genotypes were euthanized on day 11–12 after birth. AST was measured from plasma. Data are shown as box and whiskers plots indicating means, 75% confidence intervals, and 95% confidence intervals. Numbers above lines show p values for group comparisons by Mann-Whitney U test (n ≥ 12 mice per group). B, Plasma concentrations of IFN-γ correlate with end-organ damage (AST). Data points show individual Tgfb1−/− mice (n = 12; r2 = 0.49; p = 0.01).